Biobank & Molecular Analysis Program
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- Our Services
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Accelerating Scientific Discovery With Expert Specimen Support
The Biobank & Molecular Analysis Program (BMAP) at 91大神 Children鈥檚 is a fully staffed, CAP-accredited. state-of-the-art facility. Our team has extensive expertise in biorepository, genomic sequencing, and molecular analysis services. We help accelerate research for clinicians, investigators, and partners locally and globally. We collaborate with leading institutions, including Thomas Jefferson University, University of Delaware, ChristianaCare, the American Lung Association, and many others.
Our biobank is one of the largest and most diverse repositories with more than 15,000 collected specimens (and growing)听in our 91大神 repository, plus an additional 500,000 specimens in the American Lung Association sponsored Lung Health Cohort repository.
Specimens听include听solid/liquid tumors, tissue, cartilage, cells, blood, stool, and more. We offer听next generation and single cell sequencing,听spatial profiling,听digital PCR, gene expression analysis, mononuclear cell and听nucleic acid听isolation听and extraction,听and other leading-edge molecular capabilities.听
We deliver high-quality, compliant specimen collection, processing, storage, and analysis services for a broad range of projects. With advanced technologies and instrumentation, we empower life-changing pediatric research.
Our Leadership
Diana Corao-Uribe, MD
Director, Biobank & Biomolecular Analysis Program听
Part of Our Core Research Infrastructure
Core labs and services at 91大神 provide essential capabilities that advance pediatric research. Explore additional resources available to investigators across the system.听
Biomedical Research Informatics Center
DELAWARE VALLEY & FLORIDA
We consult, train, and provide computational resources for researchers, offering experimental design, data mining, analysis, and software application development.
Cell Science Core
DELAWARE VALLEY
We specialize in flow cytometry, cell sorting, cell culture, and protein analysis, allowing researchers to study conditions like cancer and autoimmune disease.
Histochemistry & Tissue Processing Core
DELAWARE VALLEY
Our core lab provides researchers with detailed tissue analysis and processing services that help advance the understanding and treatment of childhood diseases.
Core Services & Infrastructure
BMAP serves as a foundational resource for researchers. With support across study design, regulatory navigation, analytics, and funding, our end-to-end capabilities drive insights that improve children鈥檚 lives.
We operate under strict HIPAA regulations, and our site is the only pediatric biobank in the Delaware Valley accredited by the College of American Pathologists (CAP).听
What We Offer
Specimen Collection & Biobanking
- Access to more than 15,000 pediatric specimens
- Patient tissues and fluids from 91大神 patients
- Blood and saliva from close relatives
- Autopsy samples (no IRB needed)
- Specimen intake and tracking
- Customizable protocols
- Long-term, ultra-low temperature storage
- Shipping and material transport support
- Consent support for clinical teams
Guidance & Support
- Protocol development
- Consent support (in special circumstances)
- Pilot project discounts
- Billing and funding options
Specimen Processing & Analysis
- Biobank specimen processing
- Plasma/serum isolation
- Mononuclear cell isolation
- Cryopreservation
- Tissue cell culture for surgery specimens
- Nucleic acid extraction and quality control
- DNA fragment analysis
- Genomic identification and profiling
- Covaris Ultrasonication
PCR & Copy Number Variation
- Digital PCR
- Real-time PCR
- SNP analysis
- Copy number analysis
Sequencing & Expression
- DNA Sanger sequencing
- Gene expression analysis
Next Generation Sequencing
- RNA-Seq (mRNA and total RNA)
- DNA-seq (16S, whole genome, and whole exome)
- Targeted custom sequencing
- Single-cell RNA sequencing
- High-throughput DNA听methylation microarray analysis (EPIC v2.0)
Spatial Omics Applications (Coming Soon)
- Spatial transcriptomics
- Spatial proteomics
- Spatial metabolomics
- Multimodal spatial analysis
Shared Instrumentation
Available for independent use after training.
- NanoDrop鈩/NanoDrop One Spectrophotometer
- Qubit Flurometer
- Beckman Biomek 4K Liquid Handlers
- QuantStudio鈩 7 Pro Real-Time PCR Systems
Clinician Research Support
Our team helps clinicians without a wet lab with a broad array of customized research support services. We can assist with:
- Project development
- Experimental design
- Internal funding sourcing
Biorepository Set-Up
We can help you set up a biorepository, including tissues and bodily fluids from our pediatric patients and blood and saliva from close family members.听
Starting a Study听
Our team provides the information and resources researchers need to conduct impactful studies. To start a study, please email us.听We鈥檒l coordinate a meeting with the appropriate experts to move your project forward. We look forward to assisting you.
听
Specimen Submission, Use & Handling
To use our services, researchers need an .
Sign in to your iLab account or register for a new account. If you have questions about your iLab account, please email us.
Specimen听Submission
To submit a specimen for processing, researchers must complete a form through iLab.
Once in iLab, navigate to听Request Services, then select the appropriate service request.
Note:听Sending specimens to an external institution requires a material transfer agreement and a data use agreement. You can access these by contacting our Office of Technology Transfer.听
If you have any questions about submitting a specimen, please听email us.听
Clinical Trials Processing听
To submit a clinical trials processing request, researchers must complete a form through iLab.
Once in iLab, navigate to听Request Services, then听Biobank Service Request. The form is called 鈥淐linical Trials Processing Services.鈥
If you have any questions about clinical trials processing, please email us.听
Specimen Use
Before using specimens, researchers must obtain approval from the 91大神听Institutional Review Board.
Consenting Process
We encourage clinical providers to leverage their patient relationships to obtain consent themselves. However, we are fully trained to assist in the consenting process if needed.听
Please email us听with questions about the consenting process.
Shipping Specimens to Our Facility
91大神 Children鈥檚 Hospital, Delaware
Biobank & Molecular Analysis Program
1600 Rockland Rd.
Biobank GD74
Wilmington, DE 19803
Phone:听(302) 298-7367
Email:听91大神Biobank@nemours.org听|听MBCore@nemours.org
Shipping notes:
- Our team is fully trained in human biospecimen shipping and we are available for advice.
- The sender pays for all shipping costs, including packaging materials.
Contact Us听
Questions? We're here for you. Contact us.听