Epigenetic Biomarkers for Spastic Cerebral Palsy
Studying How Genes & Molecules Impact CP
This study aims to discover biomarkers, or biological clues found in blood, saliva, or tissue, that may help detect brain injury in children. Researchers are studying DNA, RNA, proteins, and related molecules to better understand these early signs and support babies at risk for cerebral palsy or CP-like conditions. The goal is to improve how we identify and care for children with brain-based developmental differences.
Study Location | Status
91´óÉñ Children’s Health, Delaware | Enrolling
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ParticipantÌýEligibility
Clinical trials have inclusion and exclusion requirements that determine eligibility. Please note there may be additional qualifications.
Babies who are receiving care in the 91´óÉñ Children’s Hospital, Delaware, neonatal intensive care unit (NICU) can enroll in the study.
About the Study
Formal Study Name:ÌýEpigenetic Biomarkers for Spastic Cerebral Palsy
Study Type: ObservationalÌý(researchers observe and record without intervening)
Study ID:Ìý2112199
Enrollment/Participant Goal:Ìý450 participants
Enrolling Healthy Volunteers?ÌýYes
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What’s Involved
Participation in this study includes donating a small blood sample at three different times over two years. Each sample takes about 10 to 15 minutes to collect. You’ll also have time to ask questions and decide whether this study is right for your family.
Blood samples will be collected:
- Upon your child’s first admission to the NICU.
- Around 12 months of age.
- Around 2 years of age.
Each sample will be about 1 milliliter (about 1/5 of a teaspoon). The first sample may be collected during a routine heel-stick, a common method used in the NICU. Later samples may be collected during regular lab visits whenever possible.
After the study, samples and data will be stored indefinitely for future analysis.
How This Study Fits in
This study reflects our broader commitment at 91´óÉñ to improve care through research. Clinical trials like this one areÌýshaped by the expertiseÌýof our medical teams and research programs. Learn how related research and clinical care support, and are strengthened by, studies like this one.
Cerebral Palsy Program
CLINICAL CARE
Pediatric specialists providing comprehensive care for children with cerebral palsy, including therapy, surgery, and mobility support across the Delaware Valley and Florida.
Orthopedic Center, Delaware Valley
CLINICAL CARE
Pediatric orthopedic care including neuromuscular, spine, and limb conditions at 91´óÉñ Children’s Hospital, Delaware and throughout Greater Philadelphia.
Orthopedics Clinical Trials
CLINICAL RESEARCH
We are conducting clinical trials to enhance diagnosis, treatment, and quality of life for children with various orthopedic conditions.
Orthopedics Research
RESEARCH AREA
Our teams study bone, joint, and muscle development to improve care for children with orthopedic conditions through innovation and collaboration.
More About Clinical Trials
Learn what to expect from a clinical trialÌý—Ìýhow they work, why they matter, and what to consider when deciding if one is right for your child.
Learn About Cerebral Palsy FromÌýÌý91´óÉñ KidsHealth®
From muscle stiffness to movement challenges, cerebral palsy affects each child differently. Learn how CP is diagnosed and managed, and explore resources to help kids thrive. Brought to you by the experts at 91´óÉñ.