Cancer Clinical Trials
What We’re Studying Now
At 91´óÉñ, our clinical trials aim to improve survival, reduce side effects, and support every stage of treatment for children, teens, and young adults. We’re studying brain and solid tumors, blood cancers, transplant outcomes, and the long-term impact of treatment.Ìý
Blood Cancers (Leukemia & Lymphoma)
A Comprehensive Approach to Improve Medication Adherence in Pediatric ALL
DELAWARE VALLEY & NORTHWEST FLORIDA
Caspofungin vs. Fluconazole to Prevent Invasive Fungal Infections in Children in Chemotherapy
DELAWARE VALLEY & NORTHWEST FLORIDA
Dasatinib Added to Chemotherapy for Newly Diagnosed Philadelphia Chromosome Positive Leukemia (ALL)
DELAWARE VALLEY
Dose Escalating and Safety Trial of Metformin With Induction Chemotherapy in Lymphoblastic Leukemia
NORTHEAST FLORIDA
Evaluation of Rituximab Efficacy and Safety in Lymphoma
DELAWARE VALLEY & NORTHWEST FLORIDA
Brain & Central Nervous System Tumors
Effects of Carboplatin and Isotretinoin on Participants With High Risk Medulloblastoma
DELAWARE VALLEY & NORTHWEST FLORIDA
Reduced Dose Craniospinal Radiotherapy in Children With Medulloblastoma
DELAWARE VALLEY & NORTHWEST FLORIDA
Study of Irinotecan and Bevacizumab With Temozolomide in Children With Central Nervous System Tumors
NORTHEAST FLORIDA
Trial of Lenalidomide in Patients With Juvenile Pilocytic Astrocytomas & Optic Pathway Gliomas
DELAWARE VALLEY & NORTHWEST FLORIDA
Modafinil for Neurocognitive Recovery After Brain Tumor (Jacksonville)
NORTHEAST FLORIDA
Modafinil vs. Placebo for Cognitive Effects After Brain Tumor
DELAWARE VALLEY & NORTHEAST FLORIDA
Trial of Postradiation Chemotherapy in Patients With Newly Diagnosed Ependymoma
DELAWARE VALLEY & NORTHWEST FLORIDA
Solid Tumors
A Trial of Multimodality Therapy for Extra-Ocular Retinoblastoma
DELAWARE VALLEY
Dose Escalation of Metformin With Standard Chemotherapy Drugs in Children With Solid Tumors
DELAWARE VALLEY & NORTHEAST FLORIDA
Irinotecan/Temozolomide Antibody in Children With Refractory, Relapsed or Progressive Neuroblastoma
DELAWARE VALLEY & NORTHEAST FLORIDA
Treatment for Ewing Sarcoma Adding Topotecan to Chemotherapy
DELAWARE VALLEY & NORTHWEST FLORIDA
Trial of PO Sorafenib in Refractory or Recurrent Pediatric Solid Malignancies
DELAWARE VALLEY & NORTHEAST FLORIDA
Survivorship & Late Effects
Key Adverse Events Following Childhood Cancer
DELAWARE VALLEY, CENTRAL FLORIDA & NORTHEAST FLORIDA
National Wilms Tumor Late Effects Study
DELAWARE VALLEY, NORTHEAST FLORIDA & CENTRAL FLORIDA
Neuropsychological, Social, Emotional and Behavioral Outcomes in Children With Cancer
DELAWARE VALLEY, CENTRAL FLORIDA & NORTHEAST FLORIDA
Umbrella Long-Term Follow-Up Protocol
DELAWARE VALLEY, CENTRAL FLORIDA & NORTHEAST FLORIDA
More About Clinical Trials
Learn what to expect from a clinical trialÌý—Ìýhow they work, why they matter, and what to consider when deciding if one is right for your child.
How Research Connects to Care
Our hematology and oncology research drives new discoveries in how we diagnose, treat, and support children with cancer and blood disorders.
From new therapies to long-term follow-up, our studies help improve survival and quality of life for young patients and their families.