91大神

Center for Clinical Diagnostics

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Center for Clinical Diagnostics

Personalizing Pediatric Care Through Innovative Diagnostics

The Center for Clinical Diagnostics at 91大神 Children鈥檚 advances pediatric health care through innovative laboratory research and testing. We bridge clinical practice and research by developing and implementing specialized diagnostic assays to meet the unique needs of children.&nbsp;</p>\r\n<p>Located in Delaware Valley, our team provides high-complexity testing focused on <a href=\"/content/nemours/us/en/pediatric-research/research-labs/transplant-diagnostic-research.html\">transplant immunology</a>, <a href=\"/content/nemours/us/en/pediatric-research/research-labs/gastroenterology-clinical.html\">gastroenterology</a>, and <a href=\"/content/nemours/us/en/pediatric-research/research-labs/clinical-immunology.html\">autoimmune disorders</a>. We use the latest technologies, including multiplexed immune assays, polymerase chain reaction (PCR), and next-generation sequencing. Our results inform diagnosis, treatment, and condition management.&nbsp;</p>\r\n<p>In addition to testing services, we collaborate with researchers, participate in clinical trials, and publish impactful findings so that kids everywhere can benefit.&nbsp;</p>\r\n<p>Our work has led to new insights and assays for detecting problems like organ transplant rejection, graft-versus-host disease, viruses, and gut inflammation.&nbsp;</p>\r\n"}} id=text-773e3be7c1 class=cmp-text>

The Center for Clinical Diagnostics at 91大神 Children鈥檚 advances pediatric health care through innovative laboratory research and testing. We bridge clinical practice and research by developing and implementing specialized diagnostic assays to meet the unique needs of children.听

Located in Delaware Valley, our team provides high-complexity testing focused on transplant immunology, gastroenterology, and autoimmune disorders. We use the latest technologies, including multiplexed immune assays, polymerase chain reaction (PCR), and next-generation sequencing. Our results inform diagnosis, treatment, and condition management.听

In addition to testing services, we collaborate with researchers, participate in clinical trials, and publish impactful findings so that kids everywhere can benefit.听

Our work has led to new insights and assays for detecting problems like organ transplant rejection, graft-versus-host disease, viruses, and gut inflammation.听

Moving Research Forward: By the Numbers

With a proven track record of research excellence and innovation, the Center for Clinical Diagnostics advances pediatric medicine to improve outcomes for children.&nbsp;</p>\r\n"}} id=text-e95de8aae7 class=cmp-text>

With a proven track record of research excellence and innovation, the Center for Clinical Diagnostics advances pediatric medicine to improve outcomes for children.听

$1.3 M听听

Revenues over cost by our Transplant and Immunology<b>&nbsp;</b>Research labs</p>\r\n"}} id=text-16b0f2e19e class=cmp-text>

Revenues over cost by our Transplant and ImmunologyResearch labs

$1.2 M听听

Revenues generated by our Gastroenterology Clinical Lab</p>\r\n"}} id=text-13d8c5f0a0 class=cmp-text>

Revenues generated by our Gastroenterology Clinical Lab

3

Diagnostic labs in our center</p>\r\n"}} id=text-cd49d0ba82 class=cmp-text>

Diagnostic labs in our center

We are&nbsp;<b>self-funding center that works with clinicians to identify, develop, and implement</b>&nbsp;high-complexity specialty tests.</p>\r\n"}} id=text-355012f505 class=cmp-text>

We are听self-funding center that works with clinicians to identify, develop, and implement听high-complexity specialty tests.


We鈥檝e&nbsp;<b>developed innovative transplant monitoring assays, and implemented rapid COVID-19 testing, </b>directly impacting children's health worldwide.</p>\r\n"}} id=text-6b95b297cf class=cmp-text>

We鈥檝e听developed innovative transplant monitoring assays, and implemented rapid COVID-19 testing, directly impacting children's health worldwide.


Our&nbsp;<b>research explores crucial areas</b>&nbsp;in transplant rejection, autoimmune disorders, and gastrointestinal disease.&nbsp;</p>\r\n"}} id=text-eeb2d2b5a8 class=cmp-text>

Our听research explores crucial areas听in transplant rejection, autoimmune disorders, and gastrointestinal disease.听


We鈥檙e&nbsp;<b>recognized for our passion to advance children鈥檚 health and well-being.</b>&nbsp;Our leadership was awarded Researcher of the Year at 91大神 for his contributions.&nbsp;</p>\r\n"}} id=text-b4b973bbc8 class=cmp-text>

We鈥檙e听recognized for our passion to advance children鈥檚 health and well-being.听Our leadership was awarded Researcher of the Year at 91大神 for his contributions.听

Leadership Team

Headshot
Paul T. Fawcett, PhD</h2>\r\n"}} id=text-fcfd070c9d class=cmp-text>

Paul T. Fawcett, PhD

Director, Center for Clinical Diagnostics</h3>\r\n<h3>Principal Research Scientist</h3>\r\n"}} id=text-1048eba960 class=cmp-text>

Director, Center for Clinical Diagnostics

Principal Research Scientist

Advancing Pediatric Medicine Through Specialized Diagnostics

A
Our research transforms laboratory discoveries into practical diagnostic solutions for children. Our work enables more precise and personalized pediatric care.</p>\r\n<h2>Focus Areas &amp; Themes</h2>\r\n<p>Our center focuses on developing and offering high-complexity pediatric diagnostic testing. Our mission is to bring the latest research advancements to clinical practice, improving patient care through innovative lab testing.&nbsp;We focus on:</p>\r\n<ul>\r\n<li><a href=\"/content/nemours/us/en/pediatric-research/research-labs/transplant-diagnostic-research.html\"><b>Transplant monitoring</b></a>: Developing and performing specialized tests to support transplant patients, such as assays to monitor for infection, rejection, and graft-versus-host disease.&nbsp;</li>\r\n<li><a href=\"/content/nemours/us/en/pediatric-research/research-labs/clinical-immunology.html\"><b>Autoimmunity and inflammation</b></a>: Creating autoantibody profile panels to facilitate faster diagnosis and management of systemic autoimmune disorders, lupus, vasculitis, and rheumatoid arthritis.&nbsp;</li>\r\n<li><a href=\"/content/nemours/us/en/pediatric-research/research-labs/gastroenterology-clinical.html\"><b>Gastroenterology health</b></a>: Advancing diagnostic testing for gastrointestinal and nutritional issues like enzyme deficiencies, gut inflammation, and pulmonary impacts.</li>\r\n<li><b>Researcher collaboration</b>: Identifying needs and opportunities for new pediatric tests.</li>\r\n</ul>\r\n"}} id=text-05bbb8a64e class=cmp-text>

Our research transforms laboratory discoveries into practical diagnostic solutions for children. Our work enables more precise and personalized pediatric care.

Focus Areas & Themes

Our center focuses on developing and offering high-complexity pediatric diagnostic testing. Our mission is to bring the latest research advancements to clinical practice, improving patient care through innovative lab testing.听We focus on:

  • Transplant monitoring: Developing and performing specialized tests to support transplant patients, such as assays to monitor for infection, rejection, and graft-versus-host disease.听
  • Autoimmunity and inflammation: Creating autoantibody profile panels to facilitate faster diagnosis and management of systemic autoimmune disorders, lupus, vasculitis, and rheumatoid arthritis.听
  • Gastroenterology health: Advancing diagnostic testing for gastrointestinal and nutritional issues like enzyme deficiencies, gut inflammation, and pulmonary impacts.
  • Researcher collaboration: Identifying needs and opportunities for new pediatric tests.

Laboratory Research

Our research labs develop and validate cutting-edge diagnostic tests across key areas. Our goal is to translate promising biomarker discoveries and analytical methods into clinically useful tests that allow for a more personalized diagnosis and treatment. Specific research involves:&nbsp;</p>\r\n<ul>\r\n<li>Measuring cytokines involved in transplant rejection</li>\r\n<li>Optimizing autoantibody testing using multiplex assays to diagnose autoimmune conditions</li>\r\n<li>Validating stool and blood tests for digestive enzyme deficiencies, celiac disease markers and gut inflammation</li>\r\n<li>Leveraging technologies like PCR, ELISA, and Luminex platforms</li>\r\n</ul>\r\n"}} id=text-d9e2eb94a7 class=cmp-text>

Our research labs develop and validate cutting-edge diagnostic tests across key areas. Our goal is to translate promising biomarker discoveries and analytical methods into clinically useful tests that allow for a more personalized diagnosis and treatment. Specific research involves:听

  • Measuring cytokines involved in transplant rejection
  • Optimizing autoantibody testing using multiplex assays to diagnose autoimmune conditions
  • Validating stool and blood tests for digestive enzyme deficiencies, celiac disease markers and gut inflammation
  • Leveraging technologies like PCR, ELISA, and Luminex platforms

Clinical Trials & Research Studies at 91大神

Pediatric clinical trials and research studies are important for advancing medical knowledge and improving care for kids around the world. Our researchers lead clinical research to study new drugs, treatments, devices, and techniques. We also contribute to national registries and collaboratives to further research in this area. Find a clinical trial or study now.</p>\r\n"}} id=text-5fac2e109d class=cmp-text>

Pediatric clinical trials and research studies are important for advancing medical knowledge and improving care for kids around the world. Our researchers lead clinical research to study new drugs, treatments, devices, and techniques. We also contribute to national registries and collaboratives to further research in this area. Find a clinical trial or study now.

Medical
Research&nbsp;Partnerships</h2>\r\n"}} id=text-51020128fc class=cmp-text>

Research听Partnerships

We expand our knowledge and leverage diverse perspectives with partnerships and collaborations within and outside our field of study.&nbsp;</p>\r\n<p>We work with 91大神 specialists in orthopedics, rheumatology, gastroenterology, solid organ transplant, and bone marrow transplant. Our team also collaborates with Children鈥檚 Hospital of Philadelphia.&nbsp;</p>\r\n"}} id=text-47e36b50e5 class=cmp-text>

We expand our knowledge and leverage diverse perspectives with partnerships and collaborations within and outside our field of study.听

We work with 91大神 specialists in orthopedics, rheumatology, gastroenterology, solid organ transplant, and bone marrow transplant. Our team also collaborates with Children鈥檚 Hospital of Philadelphia.听

Related Research & Clinical Focus

Centers at 91大神 often align with research areas, affiliated labs, and clinical programs to support discovery and care systemwide.&nbsp;</p>\r\n"}} id=text-45c0406768 class=cmp-text>

Centers at 91大神 often align with research areas, affiliated labs, and clinical programs to support discovery and care systemwide.听

Blood Disorders Research

RESEARCH AREA

We explore blood disorders in children to advance care and outcomes through innovation in diagnostics, treatment, and long-term disease management.

Cancer Research

RESEARCH AREA

Investigators study childhood cancers to improve diagnosis, treatment, and survivorship through discovery science, clinical trials, and systemwide collaboration.

Cardiac Research

RESEARCH AREA

Our researchers study congenital and acquired heart conditions to advance pediatric cardiology through innovation in diagnosis, treatment, and outcomes.

Clinical & Research Immunology Lab

DELAWARE VALLEY

Our lab provides antibody testing for pediatric autoimmune and immunological disorders using advanced methods and rapid, reliable results.

Gastroenterology Clinical Lab

DELAWARE VALLEY

Our team studies diagnostic tools and treatments for intestinal injury, pancreatic dysfunction, gastric reflux-related aspiration, celiac disease, and IBD.

Immunology Research

RESEARCH AREA

We investigate immune system function in children to advance understanding of autoimmune disease, allergy, immunodeficiency, and immunotherapy.

Pulmonology Research

RESEARCH AREA

Our teams explore lung development and respiratory disease to improve care for children through imaging, monitoring tools, and treatment innovation.

Transplant Diagnostic & Research Lab

DELAWARE VALLEY

Our lab advances pediatric care through innovative diagnostic testing and research that connects scientific discovery with clinical decision-making.