\r\n<li><a href=\"/content/nemours/us/en/locations/wilmington-ai-dupont-childrens-hospital.html\">Delaware Hospital</a></li>\r\n<li><a href=\"/content/nemours/us/en/locations/orlando-nemours-childrens-hospital.html\">Orlando Hospital</a></li>\r\n<li><a href=\"/content/nemours/us/en/locations/primary-care.html\">Primary Care Locations</a></li>\r\n</ul>\r\n"}} id=text-aa6859071a class=cmp-text>
91´óÉñ Center for Eosinophilic GI Disease
Contact Us
91´óÉñ Center for Eosinophilic GI Disease
ON THIS PAGE:
- Overview
- Patients and Families
- Meet the Team
- Clinical Trials & Studies
- For Researchers
Innovative Care and Research for Eosinophilic Esophagitis
Kids with eosinophilic esophagitis (EoE) have inflammation of the esophagus (the tube that connects the mouth to the stomach).ÌýThis inflammation can make eating difficult or uncomfortable, and create other medical issues. Most people with eosinophilic (<i>ee-eh-sin-eh-FIL-ik</i>) esophagitis (<i>eh-sof-eh-JYE-tis</i>) improve with treatment.ÌýOur pediatric team will provide state of the art, personalized care for your child. We're also advancing EoE care for all kids through research.Ìý</p>\r\n"}} id=text-34ef2657e7 class=cmp-text>
Kids with eosinophilic esophagitis (EoE) have inflammation of the esophagus (the tube that connects the mouth to the stomach).ÌýThis inflammation can make eating difficult or uncomfortable, and create other medical issues. Most people with eosinophilic (ee-eh-sin-eh-FIL-ik) esophagitis (eh-sof-eh-JYE-tis) improve with treatment.ÌýOur pediatric team will provide state of the art, personalized care for your child. We're also advancing EoE care for all kids through research.Ìý
Advanced Care With Less Wait, Kids-Only Experts and More
Our pediatric GI Center of Excellence offers families convenience and expertise, including:</p>\r\n<ul>\r\n<li>we're one of the few places in the nation that offers unsedated transnasal endoscopy (TNE) for kids<br>\r\n</li>\r\n<li>testing and on-site care from our experts in pediatric allergy & immunology<br>\r\n</li>\r\n<li>personalized plans from registered dietitians with special training in the needs of kids with EoE</li>\r\n<li>programs and clinical trials led by GI experts with decades of experience caring for children</li>\r\n</ul>\r\n"}} id=text-6474fb64a0 class=cmp-text>
Our pediatric GI Center of Excellence offers families convenience and expertise, including:
- we're one of the few places in the nation that offers unsedated transnasal endoscopy (TNE) for kids
- testing and on-site care from our experts in pediatric allergy & immunology
- personalized plans from registered dietitians with special training in the needs of kids with EoE
- programs and clinical trials led by GI experts with decades of experience caring for children
Pediatric Care From Providers Who Are Leaders in Their Field</h2>"}} id=text-6b59f61dea class=cmp-text>
Pediatric Care From Providers Who Are Leaders in Their Field
Designed for Families to Be a Center of Excellence
Your Support Changes Lives</h2>\r\n"}} id=text-c6ce328eb6 class=cmp-text>
Your Support Changes Lives
Your donations will help improve clinical care through research. Our active research program is focused on understanding why some patients do not respond well to standard therapies. In the near future, we will use what we learned from our research to develop a precision medicine approach tailored for each individual. Right drug, right patient, right time.</p>\r\n"}} id=text-03aa604e56 class=cmp-text>
Your donations will help improve clinical care through research. Our active research program is focused on understanding why some patients do not respond well to standard therapies. In the near future, we will use what we learned from our research to develop a precision medicine approach tailored for each individual. Right drug, right patient, right time.
“We're beyond grateful to Dr. Franciosi for getting the transnasal endoscopy started. My son's had 17 regular endoscopies…TNE was so fast and simple!\"</p>"}} id=text-4c01064b59 class=cmp-text>
“We're beyond grateful to Dr. Franciosi for getting the transnasal endoscopy started. My son's had 17 regular endoscopies…TNE was so fast and simple!"
\"I really liked having the TNE… I was happy to not have to deal with the anesthesia…I got to watch a movie and the procedure didn't feel bad at all!\"</p>"}} id=text-0fd2011b22 class=cmp-text>
"I really liked having the TNE… I was happy to not have to deal with the anesthesia…I got to watch a movie and the procedure didn't feel bad at all!"
Does Your Child Have Eosinophilic Esophagitis?
Schedule a consultation with a specialist to determine if your child’s symptoms are due to EoE and to learn more about our clinical services and research. We're here to help.</p>\r\n"}} id=text-0c837e774e class=cmp-text>
Schedule a consultation with a specialist to determine if your child’s symptoms are due to EoE and to learn more about our clinical services and research. We're here to help.
Center for Eosinophilic GI Disease</h2>\r\n"}} id=text-a0f543cb9e class=cmp-text>
Center for Eosinophilic GI Disease
<strong>at 91´óÉñ Children's Hospital, Florida</strong></h3>\r\n<p>6535 91´óÉñ Parkway<br>\r\nOrlando, FL 32827</p>\r\n<p><strong>Hours<br>\r\n </strong>Monday–Friday, 8 a.m. to 5 p.m.</p>\r\n<p>Our programs are staffed by pediatric specialists trained to provide care specifically for children, from newborns to age 18.</p>\r\n"}} id=text-48e1738124 class=cmp-text>
at 91´óÉñ Children's Hospital, Florida
6535 91´óÉñ Parkway
Orlando, FL 32827
Hours
Monday–Friday, 8 a.m. to 5 p.m.
Our programs are staffed by pediatric specialists trained to provide care specifically for children, from newborns to age 18.
A Team to Care for Your Child's EoE
We have a multidisciplinary Center for Eosinophilic GI Disease team that includes physicians, nurse practitioners, psychologists, social workers, nurses, research assistants and registered dietitians. We offer comprehensive GI and allergy care including unsedated transnasal endoscopy, traditional endoscopy, EndoflipTM, allergy testing, nutritional counseling and innovative clinical trials.</p>\r\n"}} id=text-f44eda7a1c class=cmp-text>
We have a multidisciplinary Center for Eosinophilic GI Disease team that includes physicians, nurse practitioners, psychologists, social workers, nurses, research assistants and registered dietitians. We offer comprehensive GI and allergy care including unsedated transnasal endoscopy, traditional endoscopy, EndoflipTM, allergy testing, nutritional counseling and innovative clinical trials.
Plan Your Visit to Our Center for Eosinophilic GI Disease</h2>\r\n"}} id=text-e3489b767d class=cmp-text>
Plan Your Visit to Our Center for Eosinophilic GI Disease
Plan a visit to our center located at 91´óÉñ Children's Hospital, Florida in Orlando. Or see or one of our GI specialists throughout Florida.</p>\r\n"}} id=text-6da61d8e36 class=cmp-text>
Plan a visit to our center located at 91´óÉñ Children's Hospital, Florida in Orlando. Or see or one of our GI specialists throughout Florida.
We Make Care Easy With 91´óÉñ Children’s MyChart</h2>\r\n"}} id=text-f748b4ea01 class=cmp-text>
We Make Care Easy With 91´óÉñ Children’s MyChart
91´óÉñ Children’s MyChart can help you easily manage your child’s main condition or concern, as well manage other aspects of your child’s health care. MyChart is interactive, so it quickly assesses how your child is doing, and tells you what steps you should take. It also lets you communicate with your care team, track appointments and symptoms, access your child’s medical records, and launch video doctor visits on demand.</p>\r\n"}} id=text-bfea8631d1 class=cmp-text>
91´óÉñ Children’s MyChart can help you easily manage your child’s main condition or concern, as well manage other aspects of your child’s health care. MyChart is interactive, so it quickly assesses how your child is doing, and tells you what steps you should take. It also lets you communicate with your care team, track appointments and symptoms, access your child’s medical records, and launch video doctor visits on demand.
Does Your Child Have Eosinophilic Esophagitis?
Learn more about EoE from information developed or curated by our experts. See a pediatric specialist to find out if your child's symptoms are due to EoE. We're here to help at EoEorlando@nemours.org.
James P. Franciosi, MD, MS, MSCE, FAAP</h2>\r\n"}} id=text-008fb9af12 class=cmp-text>
James P. Franciosi, MD, MS, MSCE, FAAP
Chief, Division of Gastroenterology, Hepatology and Nutrition <br>\r\n91´óÉñ Children's Hospital, Florida<br>\r\nProfessor of Pediatrics, University of Central Florida College of Medicine</p>\r\n<p><a href=\"/content/nemours/us/en/services/pediatric-gi-center/james-franciosi.html\">Read Dr. Franciosi's Message of Hope for Eoe Patients</a></p>\r\n"}} id=text-869dfc4cb0 class=cmp-text>
Chief, Division of Gastroenterology, Hepatology and NutritionÂ
91´óÉñ Children's Hospital, Florida
Professor of Pediatrics, University of Central Florida College of Medicine
Hadeel Alatrash Haddad, MD, MRCPCH</h2>\r\n"}} id=text-94df9d1ea9 class=cmp-text>
Hadeel Alatrash Haddad, MD, MRCPCH
Division of Gastroenterology<br />\r\nHepatology and Nutrition<br />\r\n91´óÉñ Children's Health, Orlando<br />\r\n</p>\r\n"}} id=text-3f77aa15da class=cmp-text>
Division of Gastroenterology
Hepatology and Nutrition
91´óÉñ Children's Health, Orlando
Beth Long, PsyD</h2>\r\n"}} id=text-7f52c6f9f9 class=cmp-text>
Beth Long, PsyD
Division of Pediatric Behavioral Health<br />\r\n91´óÉñ Children's Health, Lake Nona Medical City</p>\r\n"}} id=text-9fa4f22cdc class=cmp-text>
Division of Pediatric Behavioral Health
91´óÉñ Children's Health, Lake Nona Medical City
Ed Mougey, PhD</h2>\r\n"}} id=text-6cdd6e7c0c class=cmp-text>
Ed Mougey, PhD
Research Scientist<br />\r\n Department of Research, North Florida<br />\r\n 91´óÉñ Children’s Health, Jacksonville</p>\r\n"}} id=text-acde6a4ad7 class=cmp-text>
Research Scientist
Department of Research, North Florida
91´óÉñ Children’s Health, Jacksonville
Kimberly Howard, MOTR/L</h2>\r\n"}} id=text-dcf90e7e21 class=cmp-text>
Kimberly Howard, MOTR/L
Occupational Therapist<br />\r\nDepartment of Therapeutic and Rehab Services</p>\r\n"}} id=text-fe41126fbb class=cmp-text>
Occupational Therapist
Department of Therapeutic and Rehab Services
Aimee Molineaux, RD, LD</h2>\r\n"}} id=text-3cb7ea72cd class=cmp-text>
Aimee Molineaux, RD, LD
Registered Dietitian<br />\r\nDivision of Gastroenterology<br />\r\nHepatology and Nurtrition</p>\r\n"}} id=text-63316d7411 class=cmp-text>
Registered Dietitian
Division of Gastroenterology
Hepatology and Nurtrition
Our research is all about our patients.
We offer cutting edge diagnostic procedures and treatment for EoE, including unsedated transnasal endoscopy (TNE) for kids. Our technology supports our care and offers convenience for patient families with options such as telehealth visits and direct email with your child's provider via <a href=\"/content/nemours/us/en/patientfamily/nemours-mychart.html\">91´óÉñ Children's MyChart</a>. </p>\r\n<h3>What is a clinical trial? </h3>\r\n<p>A clinical trial is how researchers and medical professionals find out if a new drug, diet, device, or other medical treatment is both safe and effective. A clinical trial may compare a new treatment to an existing one. Or, it may compare a new medicine to a placebo (a medicine that has no active ingredients). Sometimes clinical trials compare new treatments to no intervention at all.</p>\r\n"}} id=text-83a08baeba class=cmp-text>
We offer cutting edge diagnostic procedures and treatment for EoE, including unsedated transnasal endoscopy (TNE) for kids. Our technology supports our care and offers convenience for patient families with options such as telehealth visits and direct email with your child's provider via 91´óÉñ Children's MyChart.Ìý
What is a clinical trial?Â
A clinical trial is how researchers and medical professionals find out if a new drug, diet, device, or other medical treatment is both safe and effective. A clinical trial may compare a new treatment to an existing one. Or, it may compare a new medicine to a placebo (a medicine that has no active ingredients). Sometimes clinical trials compare new treatments to no intervention at all.
FREoE Study</h2>\r\n"}} id=text-89d0d09166 class=cmp-text>
FREoE Study
The FREoE study is a novel diet study for children ages 2 to 18 who suffer from symptoms of EoE. Although there is increasing evidence that consumption of food additives may impact health, scientists have not tested how food additives influence clinical outcomes in EoE. While elimination of dairy from the diet provides relief for some EoE patients, we are interested in whether elimination of both common food additives and dairy from the diet results in even better outcomes for EoE patients.</p>\r\n"}} id=text-85f6fbf1bb class=cmp-text>
The FREoE study is a novel diet study for children ages 2 to 18 who suffer from symptoms of EoE. Although there is increasing evidence that consumption of food additives may impact health, scientists have not tested how food additives influence clinical outcomes in EoE. While elimination of dairy from the diet provides relief for some EoE patients, we are interested in whether elimination of both common food additives and dairy from the diet results in even better outcomes for EoE patients.
PPIREoE Study</h2>\r\n"}} id=text-a354ef75eb class=cmp-text>
PPIREoE Study
Proton pump inhibitors (PPIs) are one of the approved therapies for treatment of eosinophilic esophagitis. A large percentage of EoE patients fail to respond to PPIs due to a complex mix of environmental and genetic factors that are unique to the individual. Dr. Franciosi is leading a group of internationally recognized EoE researchers to identify factors that limit response to PPIs in EoE and will use this information to improve individual response.</p>\r\n"}} id=text-6bcf8880bd class=cmp-text>
Proton pump inhibitors (PPIs) are one of the approved therapies for treatment of eosinophilic esophagitis. A large percentage of EoE patients fail to respond to PPIs due to a complex mix of environmental and genetic factors that are unique to the individual. Dr. Franciosi is leading a group of internationally recognized EoE researchers to identify factors that limit response to PPIs in EoE and will use this information to improve individual response.
PPI Precision Medicine Study</h2>\r\n"}} id=text-f24ea846d1 class=cmp-text>
PPI Precision Medicine Study
For every drug therapy that is currently on the market, a percentage of the patients who receive the therapy will respond poorly due to variability in individual environmental and genetic factors. Precision medicine is the study of the factors that associate with poor therapeutic response and the use of this information to improve therapeutic outcomes. This study seeks to establish precision medicine recommendations for drug therapies that are routinely used to treat gastrointestinal (GI) conditions.ÌýÂ </p>\r\n"}} id=text-5b557f7bec class=cmp-text>
For every drug therapy that is currently on the market, a percentage of the patients who receive the therapy will respond poorly due to variability in individual environmental and genetic factors. Precision medicine is the study of the factors that associate with poor therapeutic response and the use of this information to improve therapeutic outcomes. This study seeks to establish precision medicine recommendations for drug therapies that are routinely used to treat gastrointestinal (GI) conditions.ÌýÂ
“We're beyond grateful to Dr. Franciosi for getting the transnasal endoscopy started. My son's had 17 regular endoscopies…TNE was so fast and simple!\"</p>"}} id=text-627f41f10d class=cmp-text>
“We're beyond grateful to Dr. Franciosi for getting the transnasal endoscopy started. My son's had 17 regular endoscopies…TNE was so fast and simple!"
Donations That Help Change Lives</h2>\r\n"}} id=text-2c589bab05 class=cmp-text>
Donations That Help Change Lives
Your donations will help improve clinical care through research. Our active research program is focused on understanding why some patients do not respond well to standard therapies. In the near future, we will use what we learned from our research to develop a precision medicine approach tailored for each individual. Right drug, right patient, right time.</p>\r\n"}} id=text-570c85434f class=cmp-text>
Your donations will help improve clinical care through research. Our active research program is focused on understanding why some patients do not respond well to standard therapies. In the near future, we will use what we learned from our research to develop a precision medicine approach tailored for each individual. Right drug, right patient, right time.
Our Research Is All About Our Patients
Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact our research team with additional questions at the contacts provided.Ìý</p>\r\n"}} id=text-b82c5f95cf class=cmp-text>
Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact our research team with additional questions at the contacts provided.Ìý
We Are a Resource Center For Researchers
Whether you have a question about our clinical care, research, or general condition or institutional questions, we're here to help. You can also contact us for things such as access to REDCap data entry, Protocols, Manual of Procedures, forms and progress reports on studies.</p>\r\n<p>Please specify which study you are inquiring about when contacting our team. We look forward to collaborating with you to improve the health of all children for many generations to come.Ìý</p>\r\n"}} id=text-c61c5d20fb class=cmp-text>
Whether you have a question about our clinical care, research, or general condition or institutional questions, we're here to help. You can also contact us for things such as access to REDCap data entry, Protocols, Manual of Procedures, forms and progress reports on studies.
Please specify which study you are inquiring about when contacting our team. We look forward to collaborating with you to improve the health of all children for many generations to come.Ìý
Get Involved or Enroll in Our Research Studies</h2>\r\n"}} id=text-718c869de4 class=cmp-text>
Get Involved or Enroll in Our Research Studies
We are changing the outcome together. Beyond providing unmatched clinical care, we are working around the clock to advance eosinophilic esophagitis (EoE) innovation and research.</p>\r\n"}} id=text-df877dc2dc class=cmp-text>
We are changing the outcome together. Beyond providing unmatched clinical care, we are working around the clock to advance eosinophilic esophagitis (EoE) innovation and research.
How Genetic Variations Influence PPI Therapy
<strong>James Franciosi, MD, MS, MSCE<br />\r\n How Genetic Variations Influence PPI Therapy in Pediatric EoE</strong></p>\r\n<p>Dr. Franciosi, who leads the Eosinophilic GI Disease Center at 91´óÉñ Children’s Hospital, Florida, discusses the prevalence of pediatric eosinophilic esophagitis (EoE), his research on how genetic variations can differentiate responses to proton-pump inhibitor therapy in pediatric EoE, and more.</p>\r\n"}} id=text-93f2ee2bff class=cmp-text>
James Franciosi, MD, MS, MSCE
How Genetic Variations Influence PPI Therapy in Pediatric EoE
Dr. Franciosi, who leads the Eosinophilic GI Disease Center at 91´óÉñ Children’s Hospital, Florida, discusses the prevalence of pediatric eosinophilic esophagitis (EoE), his research on how genetic variations can differentiate responses to proton-pump inhibitor therapy in pediatric EoE, and more.
Eosinophilic Esophagitis: It Takes A Village
<strong><i>Presentation by Dr. James Franciosi (GI)<br />\r\n Dr. Jordan Smallwood (Allergy & Immunology) <br />\r\n Edward Mougey, PhD (Research Scientist)</i></strong></p>\r\n<p>This presentaion includes highlights from the EoE GI Disease program such as initial research findings related to pharmacogenetics and pharmacokinetics of PPI treatments for EoE, the importance of multidisclplinary coordnation for diagnosis and treatment of EoE, and the 91´óÉñ EoE Center of Excellence.Ìý</p>\r\n"}} id=text-0800a7b09c class=cmp-text>
Presentation by Dr. James Franciosi (GI)
Dr. Jordan Smallwood (Allergy & Immunology)
Edward Mougey, PhD (Research Scientist)
This presentaion includes highlights from the EoE GI Disease program such as initial research findings related to pharmacogenetics and pharmacokinetics of PPI treatments for EoE, the importance of multidisclplinary coordnation for diagnosis and treatment of EoE, and the 91´óÉñ EoE Center of Excellence.Ìý
Would You Like to Be Part of Our Research Team?
If you are a clinical researcher who is participating in one of our research studies and would like to set up an account for web access, or if you would like request access to research resources, please click the "Request Access" button below.</p>\r\n"}} id=text-3761760184 class=cmp-text>
If you are a clinical researcher who is participating in one of our research studies and would like to set up an account for web access, or if you would like request access to research resources, please click the "Request Access" button below.